Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550151 | 0.85 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL26908781 | 0.84 | TTR (0.64) | TTRCYP2C9USP2LMNATBXA2R | |
| Acetic Acid SCHEMBL27749791 | 0.84 | TTR (0.64) | TTRCYP2C9USP2LMNATBXA2R | |
| Hydrochloric Acid SCHEMBL28376706 | 0.83 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL23158570 | 0.83 | TTR (0.59) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13265744 | 0.83 | TTR (0.59) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL6431084 | 0.83 | TTR (0.71) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL23158590 | 0.82 | TTR (0.58) | TTRCYP2C9USP2LMNATBXA2R | |
| Acetic Acid SCHEMBL28298005 | 0.82 | TTR (0.70) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL10844751 | 0.82 | TTR (0.70) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937262-B2 | Prodrugs of naproxen and diclofenac | LARSEN, CLAUS SELCH (DK) | 2018-04-10 | — | — | US | disclosed |
| US-9937262-B2 | Prodrugs of naproxen and diclofenac | LARSEN, CLAUS SELCH (DK) | 2018-04-10 | — | — | US | disclosed |
| US-9937262-B2 | Prodrugs of naproxen and diclofenac | LARSEN, CLAUS SELCH (DK) | 2018-04-10 | — | — | US | disclosed |
| US-9809557-B2 | Prodrugs of non-steroid anti-inflammatory agents (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2017-11-07 | — | — | US | disclosed |
| US-9809557-B2 | Prodrugs of non-steroid anti-inflammatory agents (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2017-11-07 | — | — | US | disclosed |
| US-9809557-B2 | Prodrugs of non-steroid anti-inflammatory agents (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2017-11-07 | — | — | US | disclosed |
| EP-2991682-B1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | SELCH LARSEN CLAUS (DK) | 2017-04-19 | — | — | EP | disclosed |
| EP-2991682-B1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | SELCH LARSEN CLAUS (DK) | 2017-04-19 | — | — | EP | disclosed |
| EP-2773378-B1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2016-08-10 | — | — | EP | disclosed |
| US-20160074523-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | LARSEN, CLAUS SELCH (DK) | 2016-03-17 | — | — | US | disclosed |
| US-20160074523-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | LARSEN, CLAUS SELCH (DK) | 2016-03-17 | — | — | US | disclosed |
| US-20160074523-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | LARSEN, CLAUS SELCH (DK) | 2016-03-17 | — | — | US | disclosed |
| EP-2991682-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | Larsen, Claus Selch (DK) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177479-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | SELCH LARSEN CLAUS (DK) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014177479-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | SELCH LARSEN CLAUS (DK) | 2014-11-06 | — | — | WO | disclosed |
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2014-10-23 | — | — | US | disclosed |
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2014-10-23 | — | — | US | disclosed |
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2014-10-23 | — | — | US | disclosed |
| EP-2773378-A1 | PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS) | Larsen, Claus Selch (DK) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064153-A1 | PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | MMP1, MIF, CYP21A2 | TTR 2689/4885CYP2C9 150/4885USP2 593/4885 |
| US-20160074523-A1 | PRODRUGS OF NAPROXEN AND DICLOFENAC | CYP2D6, CYP2U1, PTGER1 | TTR 1236/4885CYP2C9 30/4885USP2 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.