Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550151 | 0.89 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13089998 | 0.87 | TTR (0.64) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13089885 | 0.87 | TTR (0.64) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13089883 | 0.86 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13089795 | 0.86 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13240140 | 0.85 | TTR (0.56) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL14920437 | 0.83 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL26908781 | 0.83 | TTR (0.64) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13089839 | 0.82 | PTGS2 (0.60) | TTRCYP2C9USP2LMNATBXA2R | |
| Hydrochloric Acid SCHEMBL28376706 | 0.82 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759392-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20090170941-A1 | Pharmaceutical Compounds | NICOX S.A. (FR) | 2009-07-02 | — | — | US | disclosed |
| US-7399878-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2008-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170941-A1 | Pharmaceutical Compounds | NR0B2, NR0B1, CYP11B2 | TTR 687/4885CYP2C9 194/4885USP2 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.