Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.54 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921065 | 0.94 | C5AR1 (0.49) | C5AR1NTSR2NTSR1SORT1CTSL | |
| SCHEMBL30504860 | 0.94 | C5AR1 (0.52) | C5AR1NTSR2NTSR1SORT1CTSL | |
| SCHEMBL31409175 | 0.93 | C5AR1 (0.53) | C5AR1NTSR2NTSR1SORT1APLNR | |
| SCHEMBL30512749 | 0.91 | NPY2R (0.55) | C5AR1APLNR | |
| SCHEMBL30230017 | 0.90 | OPRM1 (0.58) | CTSLCTSSCTSKCTSHOPRM1 | |
| SCHEMBL29608118 | 0.90 | C5AR1 (0.59) | C5AR1NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL29608007 | 0.90 | C5AR1 (0.59) | C5AR1NTSR2NTSR1SORT1OPRM1 | |
| SCHEMBL29634905 | 0.90 | AGTR1 (0.56) | C5AR1NTSR2NTSR1SORT1 | |
| SCHEMBL29607931 | 0.90 | C5AR1 (0.55) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29608041 | 0.90 | C5AR1 (0.58) | C5AR1NTSR2NTSR1SORT1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109806395-A | Medical usage | 瓦力雷克斯有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-104136082-B | medical use | 瓦力雷克斯有限公司 | 2019-03-08 | — | — | CN | disclosed |
| EP-2991662-A2 | MODULATORS OF THE SRC-KINASE ACTIVITY FOR PREVENTING OR TREATING METASTATIC CANCER | Cancer Research Technology Ltd (GB) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177868-A2 | MEDICAL USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-11-06 | — | — | WO | disclosed |