Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289271 | 1.00 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3697380 | 0.87 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15206677 | 0.87 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28030532 | 0.81 | DPP4 (0.60) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3791188 | 0.79 | DPP4 (0.80) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL16433580 | 0.79 | DPP4 (0.55) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1288978 | 0.79 | DPP4 (0.80) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1289158 | 0.79 | DPP4 (0.80) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL29644108 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3254233 | 0.78 | DPP4 (0.64) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065066-A1 | PROCESSES FOR PREPARING 4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6- DIHYDRO [L,2,41-TRIAZOLO[43-A]PYRAZIN-7(8H)-YL]-L-(2,4,5- TRIFLUOROPHENYL)BUTAN-2-AMINE | CADILA HEALTHCARE LIMITED (IN) | 2013-05-10 | — | — | WO | disclosed |