Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | FAP | Q12884 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289241 | 0.81 | DPP4 (0.47) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL29558815 | 0.81 | DPP4 (0.67) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL214373 | 0.81 | DPP4 (0.67) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL14922003 | 0.79 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1289271 | 0.79 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28030532 | 0.77 | DPP4 (0.60) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3697380 | 0.77 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15206677 | 0.77 | DPP4 (0.65) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3254233 | 0.76 | DPP4 (0.64) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3254241 | 0.76 | DPP4 (0.64) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257686-A1 | TRANSAMINASE, IMMOBILIZED TRANSAMINASE AND USE FOR PREPARING SITAGLIPTIN | 弈柯莱生物科技(上海)股份有限公司 | 2022-12-15 | — | — | WO | disclosed |
| CN-114507699-A | Low-cost preparation method of sitagliptin phosphate | 上海微巨实业有限公司 | 2022-05-17 | — | — | CN | disclosed |