Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697380 | 0.92 | DPP4 (0.65) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL15206677 | 0.92 | DPP4 (0.65) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL18624009 | 0.79 | DPP4 (0.85) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL681952 | 0.79 | DPP4 (0.85) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL14922003 | 0.79 | DPP4 (0.56) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL1289271 | 0.79 | DPP4 (0.56) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL3254241 | 0.75 | DPP4 (0.64) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL3254233 | 0.75 | DPP4 (0.64) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL20830389 | 0.73 | DPP4 (0.75) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL26076680 | 0.72 | DPP4 (0.58) | DPP4DPP8DPP7DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946224-B2 | Substituted [1,2,4]triazolo[4,3-A]pyrazines for medicaments and pharmaceutical compositions | REDX PHARMA LIMITED (GB) | 2015-02-03 | — | — | US | disclosed |