Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.56 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | FGF1 | P05230 | 1/20 | 0.53 |
| ▸ | FGF2 | P09038 | 1/20 | 0.53 |
| ▸ | VEGFA | P15692 | 1/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922112 | 0.94 | TDP1 (0.62) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL140972 | 0.90 | TDP1 (0.72) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31224941 | 0.90 | TDP1 (0.72) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14165464 | 0.90 | TDP1 (0.72) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9926313 | 0.90 | TDP1 (0.72) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18268937 | 0.90 | TDP1 (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30256099 | 0.89 | F2 (0.65) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18257192 | 0.88 | TDP1 (0.81) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2768198 | 0.88 | TDP1 (0.81) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19959667 | 0.88 | TDP1 (0.81) | TDP1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435800-B2 | Activated labeling reagents and methods for preparing and using the same | BIOSIGHT LTD. (IL) | 2013-05-07 | — | — | US | disclosed |