Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552880 | 0.92 | F2 (0.58) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1727527 | 0.92 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13888577 | 0.92 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10002269 | 0.92 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29392244 | 0.91 | PRSS1 (0.64) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14922108 | 0.90 | TDP1 (0.62) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14922112 | 0.88 | TDP1 (0.62) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL24495340 | 0.86 | F2 (0.49) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3870139 | 0.86 | TDP1 (0.61) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14165464 | 0.84 | TDP1 (0.72) | TDP1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160346409-A1 | TARGETED MOLECULAR IMAGING CONTRAST AGENTS | UNIV MCMASTER (CA) | 2016-12-01 | — | — | US | disclosed |