Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 11/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.61 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325907 | 0.94 | ALDH1A1 (0.74) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13856604 | 0.93 | ALDH1A1 (0.71) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL14104258 | 0.93 | ALDH1A1 (0.73) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13856585 | 0.91 | PTPN7 (0.71) | ALDH1A1NPSR1MEN1KMT2APOLB | |
| SCHEMBL4670262 | 0.88 | ALDH1A1 (0.84) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL4670263 | 0.88 | ALDH1A1 (0.84) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL14104272 | 0.87 | ALDH1A1 (0.80) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13856568 | 0.87 | ALDH1A1 (0.68) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13856539 | 0.87 | PTPN22 (0.70) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13856639 | 0.86 | MEN1 (0.79) | ALDH1A1NPSR1MEN1KMT2APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436031-B2 | Transcription factor modulating compounds and methods of use thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2013-05-07 | — | — | US | disclosed |