Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 9/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.78 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.76 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.76 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.68 |
| ▸ | IL6 | P05231 | 1/20 | 0.68 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.67 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.66 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.66 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670262 | 1.00 | ALDH1A1 (0.84) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13855965 | 0.92 | ALDH1A1 (0.76) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL12325907 | 0.90 | ALDH1A1 (0.74) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL14104258 | 0.89 | ALDH1A1 (0.73) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL14922115 | 0.88 | ALDH1A1 (0.72) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL4668189 | 0.88 | MEN1 (0.82) | ALDH1A1NPSR1MEN1KMT2ADNMT1 | |
| SCHEMBL4668190 | 0.88 | MEN1 (0.82) | ALDH1A1NPSR1MEN1KMT2ADNMT1 | |
| SCHEMBL13855930 | 0.88 | MEN1 (0.71) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL13855947 | 0.88 | ALDH1A1 (0.87) | ALDH1A1NPSR1MEN1KMT2APSMD14 | |
| SCHEMBL4669050 | 0.88 | ALDH1A1 (0.78) | ALDH1A1NPSR1MEN1KMT2APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000140-A1 | Use of derivatives of 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine or of 3-oxo-2,3-dihydro-5H-imidazolo[3,2-a]pyrimidine for the preparation of pharmaceutical compositions intended for the treatment of cancer | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-12-10 | — | — | EP | disclosed |