Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922607 | 0.95 | SCN9A (0.37) | SMN1; SMN2FPR2MEN1KMT2AHPGD | |
| SCHEMBL14922667 | 0.95 | SCN9A (0.37) | SMN1; SMN2FPR2MEN1KMT2AHPGD | |
| SCHEMBL14922583 | 0.95 | SMN1; SMN2 (0.39) | SMN1; SMN2FPR2MEN1KMT2AHPGD | |
| SCHEMBL14922599 | 0.95 | SMN1; SMN2 (0.39) | SMN1; SMN2FPR2MEN1KMT2AHPGD | |
| SCHEMBL2509916 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL2513235 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL2509917 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL2513233 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL2513234 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP | |
| SCHEMBL2506394 | 0.93 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AMAPTALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |