Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922667 | 1.00 | SCN9A (0.37) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14922608 | 0.98 | SCN9A (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14922674 | 0.98 | SCN9A (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2513234 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2509916 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2509917 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2513233 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2506394 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2513235 | 0.96 | LMNA (0.38) | SCN9AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14922591 | 0.95 | SMN1; SMN2 (0.36) | SCN9AMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |