Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 17/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 16/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197216 | 0.95 | CDK9 (0.36) | CDK9CCNT1 | |
| SCHEMBL14922566 | 0.94 | CDK9 (0.34) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL12197345 | 0.90 | CDK9 (0.35) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL15381798 | 0.89 | CDK9 (0.37) | CDK9CCNT1NPC1ALDH1A1RAB9A | |
| SCHEMBL15381612 | 0.89 | CDK9 (0.37) | CDK9CCNT1NPC1ALDH1A1RAB9A | |
| SCHEMBL14922622 | 0.88 | CDK9 (0.34) | CDK9CCNT1CNR1CNR2PDE5A | |
| SCHEMBL15381714 | 0.87 | CDK9 (0.36) | CDK9CCNT1NPC1ALDH1A1RAB9A | |
| SCHEMBL15381758 | 0.87 | CDK9 (0.36) | CDK9CCNT1NPC1ALDH1A1RAB9A | |
| SCHEMBL15381622 | 0.86 | CNR2 (0.35) | CDK9CCNT1CNR1CNR2 | |
| SCHEMBL15381538 | 0.86 | CNR2 (0.35) | CDK9CCNT1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |