Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 9/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922668 | 0.96 | CDK9 (0.34) | CDK9CCNT1MEN1KMT2APDE5A | |
| SCHEMBL14922604 | 0.95 | CDK9 (0.37) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL12197212 | 0.94 | CDK9 (0.36) | CDK9CCNT1SCN9ALMNAALOX5AP | |
| SCHEMBL12197328 | 0.90 | CDK9 (0.38) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL12197196 | 0.90 | CDK9 (0.38) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL14922606 | 0.90 | MEN1 (0.32) | CDK9CCNT1MEN1KMT2ASCN9A | |
| SCHEMBL14922681 | 0.90 | MEN1 (0.32) | CDK9CCNT1MEN1KMT2ASCN9A | |
| SCHEMBL12197194 | 0.90 | CTSL (0.36) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL14922653 | 0.88 | CDK9 (0.35) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL14922607 | 0.88 | SCN9A (0.37) | MEN1KMT2ASCN9APPARDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |