Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922633 | 1.00 | GPR119 (0.36) | GPR119HCRTR2HTR2CHTR2BHTR2A | |
| SCHEMBL14922618 | 0.94 | GPR119 (0.36) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL14922632 | 0.94 | GPR119 (0.36) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL14922621 | 0.94 | GPR119 (0.39) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL14922675 | 0.94 | GPR119 (0.39) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL26209565 | 0.94 | GPR119 (0.39) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL14922576 | 0.92 | ALOX5AP (0.35) | GPR119HCRTR2HTR2CHTR2BHTR2A | |
| SCHEMBL14922665 | 0.92 | ALOX5AP (0.35) | GPR119HCRTR2HTR2CHTR2BHTR2A | |
| SCHEMBL14922688 | 0.92 | GPR119 (0.37) | GPR119HCRTR2ALOX5APFEN1SCN9A | |
| SCHEMBL14922630 | 0.92 | GPR119 (0.37) | GPR119HCRTR2ALOX5APFEN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |