Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | FEN1 | P39748 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922630 | 1.00 | GPR119 (0.37) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922632 | 0.98 | GPR119 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922618 | 0.98 | GPR119 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL12197438 | 0.95 | GPR119 (0.34) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL12197404 | 0.95 | GPR119 (0.34) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922673 | 0.92 | GPR119 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922582 | 0.92 | FEN1 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922568 | 0.92 | FEN1 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL14922633 | 0.92 | GPR119 (0.36) | GPR119SCN9AHCRTR2ALOX5APFEN1 | |
| SCHEMBL22277366 | 0.92 | GPR119 (0.33) | GPR119SCN9AHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |