Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | PNMT | P11086 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107538 | 0.86 | CYP3A4 (0.54) | PNMTCYP3A4IDO1 | |
| SCHEMBL253442 | 0.85 | CALM1 (0.48) | LTA4HSIGMAR1CYP3A4 | |
| SCHEMBL14649874 | 0.82 | CYP3A4 (0.47) | TAAR1CYP3A4IDO1 | |
| SCHEMBL24510823 | 0.82 | TAAR1 (0.46) | TAAR1PNMTLTA4HCYP3A4IDO1 | |
| SCHEMBL3300276 | 0.82 | PNMT (0.65) | TAAR1PNMTSIGMAR1CYP3A4IDO1 | |
| SCHEMBL22040237 | 0.81 | TAAR1 (0.52) | TAAR1PNMTLTA4HCYP3A4IDO1 | |
| SCHEMBL12706760 | 0.80 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL14397100 | 0.79 | SOS1 (0.47) | CYP3A4 | |
| SCHEMBL14685891 | 0.79 | TAAR1 (0.53) | TAAR1PNMTCYP3A4IDO1AGXT | |
| SCHEMBL14397402 | 0.79 | CYP3A4 (0.47) | CYP3A4IDO1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |