SCHEMBL14922780

SCHEMBL14922780

CC1=CC(=C2C=CC(=O)C=C2)C=CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
GAA P10253 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 4/20 0.38
ALDH1A1 P00352 3/20 0.38
RECQL P46063 3/20 0.38
MAPK1 P28482 3/20 0.38
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
ACHE P22303 2/20 0.38
APOBEC3G Q9HC16 2/20 0.38
BCHE P06276 1/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
CASP1 P29466 1/20 0.38
BLM P54132 1/20 0.38
MDM2 Q00987 1/20 0.38
DHODH Q02127 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ERBB2 P04626 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12112009 0.90 EEF2K (0.37) KDM4EGAAL3MBTL1TDP1ALDH1A1
SCHEMBL20824938 0.90 EEF2K (0.37) KDM4EGAAL3MBTL1TDP1ALDH1A1
Cresoquinone SCHEMBL28020551 0.85 MAOA (0.47) KDM4EGAAL3MBTL1TDP1ALDH1A1
Cresoquinone SCHEMBL49207 0.82
Cresoquinone SCHEMBL27750381 0.79 ERBB2 (0.44) KDM4EGAAL3MBTL1TDP1ALDH1A1
Cresoquinone SCHEMBL28970007 0.79 ERBB2 (0.44) KDM4EGAAL3MBTL1TDP1ALDH1A1
Cresoquinone SCHEMBL28348842 0.79 ERBB2 (0.44) KDM4EGAAL3MBTL1TDP1ALDH1A1
SCHEMBL2751602 0.72 ALDH1A1 (0.73) KDM4EGAAL3MBTL1TDP1ALDH1A1
Cresoquinone SCHEMBL28838192 0.71 ERBB2 (0.38) KDM4EGAAL3MBTL1TDP1ALDH1A1
SCHEMBL12767612 0.71 ALDH1A1 (0.41) ALDH1A1POLBMAPTHPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed