Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045003 | 0.79 | MAPT (0.48) | ESR1LMNAALDH1A1CYP3A4MAPT | |
| SCHEMBL15925520 | 0.77 | VDR (0.39) | VDRESR1 | |
| SCHEMBL14701777 | 0.77 | VDR (0.41) | VDRESR1ALDH1A1NPSR1 | |
| SCHEMBL13342735 | 0.76 | TSHR (0.51) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL21168208 | 0.76 | ELANE (0.36) | ELANEVDR | |
| SCHEMBL9338985 | 0.76 | ESR1 (0.47) | VDRESR1LMNAALDH1A1MAPT | |
| SCHEMBL22476044 | 0.76 | CYP19A1 (0.43) | VDRESR1LMNAALDH1A1CYP3A4 | |
| SCHEMBL12907945 | 0.75 | VDR (0.42) | VDRESR1ALDH1A1NPSR1 | |
| SCHEMBL14754930 | 0.75 | VDR (0.42) | VDRESR1ALDH1A1NPSR1 | |
| SCHEMBL10291402 | 0.75 | VDR (0.42) | VDRESR1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589589-A1 | TRIPHENYLAMINE DERIVATIVE | Hodogaya Chemical Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |