SCHEMBL14922956

SCHEMBL14922956

Cc1ccc(C(C)(C)c2cc(C(C)(C)c3ccc(O)cc3)cc(C(C)(C)c3ccc(O)cc3)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.70
ESR2 Q92731 7/20 0.70
CYP3A4 P08684 3/20 0.70
TSHR P16473 3/20 0.70
HPGD P15428 2/20 0.70
HSD17B10 Q99714 2/20 0.70
AR P10275 1/20 0.70
SLC6A2 P23975 1/20 0.70
SLC6A4 P31645 1/20 0.70
HTR6 P50406 1/20 0.70
ESRRG P62508 1/20 0.70
SLC6A3 Q01959 1/20 0.70
ALDH1A1 P00352 2/20 0.59
ACHE P22303 1/20 0.56
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
SHBG P04278 1/20 0.42
CNR1 P21554 3/20 0.41
CNR2 P34972 3/20 0.41
ALOX15 P16050 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822914 0.93 ESR1 (0.80) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL1101874 0.93 ESR1 (0.80) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL13609962 0.91 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL76175 0.91 ESR1 (0.84) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL822972 0.90 ESR1 (0.85) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL2385710 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL22782579 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL12299307 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL19901313 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL28059675 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9422395-B2 Multi-functional photoactive additives with improved chemical and flame resistance SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2016-08-23 US disclosed
US-9110370-B2 Photoactive additive with functionalized benzophenone SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-08-18 US disclosed
US-9091920-B2 Photosensitive siloxane resin composition MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-8993214-B2 Positive photosensitive siloxane composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2015-03-31 US disclosed
US-20140335452-A1 POSITIVE PHOTOSENSITIVE SILOXANE COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-11-13 US disclosed
US-20140335448-A1 PHOTOSENSITIVE SILOXANE RESIN COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-11-13 US disclosed
US-20140272691-A1 PHOTOACTIVE ADDITIVE WITH FUNCTIONALIZED BENZOPHENONE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 US disclosed
US-20140272347-A1 UV-CURABLE FILM COMPOSITIONS WITH IMPROVED SCRATCH RESISTANCE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 US disclosed
US-20140275324-A1 MULTI-FUNCTIONAL PHOTOACTIVE ADDITIVES WITH IMPROVED CHEMICAL AND FLAME RESISTANCE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 US disclosed
EP-2590025-B1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION FILM, AND SEMICONDUCTOR DEVICE USING THE PHOTOSENSITIVE RESIN COMPOSITION OR THE PHOTOSENSITIVE RESIN COMPOSITION FILM TORAY INDUSTRIES (JP) 2014-09-17 EP disclosed
EP-2590025-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION FILM, AND SEMICONDUCTOR DEVICE USING THE PHOTOSENSITIVE RESIN COMPOSITION OR THE PHOTOSENSITIVE RESIN COMPOSITION FILM Toray Industries, Inc. (JP) 2013-05-08 EP disclosed