Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.85 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | ESRRG | P62508 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968 | 0.92 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL14922956 | 0.90 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL22171819 | 0.90 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL13709443 | 0.89 | ESR1 (0.78) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL10411660 | 0.89 | ESR1 (0.66) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL822914 | 0.88 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL1101874 | 0.88 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| Phenol SCHEMBL1652130 | 0.86 | ESR1 (0.88) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL13059074 | 0.85 | ESR1 (0.79) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL2786793 | 0.85 | ESR1 (0.85) | ESR1ESR2CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216008-A1 | HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-20170369679-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9783655-B2 | NOR-HALS compounds as flame retardants | BASF SE (DE) | 2017-10-10 | — | — | US | disclosed |
| US-20160229989-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20150284535-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2015-10-08 | — | — | US | disclosed |
| US-20150148464-A1 | FLAME RETARDANT COMPOSITIONS OF PHOSPHINIC ACID SALTS AND NITROXYL DERIVATIVES | BASF SE (DE) | 2015-05-28 | — | — | US | disclosed |
| US-8877838-B2 | Melamine phenylphosphinate flame retardant compositions | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20140316032-A1 | P-N-COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140243455-A1 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS | BASF SE (DE) | 2014-08-28 | — | — | US | disclosed |
| US-20140238269-A1 | Optical Film | SK INNOVATION CO., LTD. (KR) | 2014-08-28 | — | — | US | disclosed |
| US-20130059952-A1 | PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | US | disclosed |
| US-8349224-B2 | Melamine phenylphosphonate flame retardant compositions | BASF SE Ludwigshafen (DE) | 2013-01-08 | — | — | US | disclosed |
| US-8236881-B2 | DOPO flame retardant compositions | BASF SE (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20120108712-A1 | PHENYLPHOSPHONATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| US-20120095140-A1 | DOPO FLAME RETARDANT COMPOSITIONS | ROTH MICHAEL (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20110294920-A1 | DOPO-FLAME RETARDANT IN EPOXY RESINS | BASF SE (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110288206-A1 | MELAMINE PHENYLPHOSPHINATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110266507-A1 | MELAMINE PHENYLPHOSPHONATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110237715-A1 | FLAME RETARDANT COMPOSITIONS OF PHOSPHINIC ACID SALTS AND NITROXYL DERIVATIVES | BASF SE (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110190428-A1 | FLAME RETARDANT COMPOSITIONS WITH POLYMERIC DISPERSING AGENTS | BASF SE (DE) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288206-A1 | MELAMINE PHENYLPHOSPHINATE FLAME RETARDANT COMPOSITIONS | PHOSPHO1, FLAD1, PFAS | ESR1 1985/4885ESR2 871/4885CYP3A4 2218/4885 |
| US-20180216008-A1 | HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS | PFAS, PCBP1, DDT | ESR1 2299/4885ESR2 2354/4885CYP3A4 1146/4885 |
| US-20170369679-A1 | NOR-HALS COMPOUNDS AS FLAME RETARDANTS | PFAS, NONO, PARG | ESR1 4170/4885ESR2 3543/4885CYP3A4 2209/4885 |
| US-20130059952-A1 | PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS | PFAS, PHOSPHO1, PIK3CA | ESR1 3454/4885ESR2 3778/4885CYP3A4 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.