Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.48 |
| ▸ | GABRP | O00591 | 4/20 | 0.45 |
| ▸ | GABRD | O14764 | 4/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.45 |
| ▸ | GABRE | P78334 | 4/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305185 | 0.82 | NPC1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16021537 | 0.78 | SLC9A1 (0.54) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13680451 | 0.69 | SOS1 (0.58) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29962351 | 0.69 | SOS1 (0.57) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28879185 | 0.69 | SOS1 (0.57) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10000785 | 0.67 | SOS1 (0.69) | SLC9A1SOS1S1PR4ALDH1A1PTGS2 | |
| SCHEMBL1544316 | 0.66 | VCP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9980406 | 0.66 | SOS1 (0.54) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3104507 | 0.66 | SLC9A1 (0.48) | SLC9A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3113402 | 0.66 | SLC9A1 (0.49) | SLC9A1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606727-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2589294-A1 | Compounds with nematicidal activity | Bayer CropScience AG (DE) | 2013-05-08 | — | — | EP | disclosed |