Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520697 | 0.83 | TRPV1 (0.41) | TRPV1GAARAB9ACHRM3ALDH1A1 | |
| SCHEMBL7528142 | 0.77 | ADAMTS5 (0.40) | TRPV1GAARAB9ACHRM3ALDH1A1 | |
| SCHEMBL7522013 | 0.76 | ADAMTS5 (0.42) | TRPV1GAACNR1CNR2GPR55 | |
| SCHEMBL8265223 | 0.74 | BACE1 (0.33) | ALDH1A1 | |
| SCHEMBL7521184 | 0.71 | HDAC3 (0.42) | ALDH1A1 | |
| SCHEMBL13475756 | 0.71 | ADAMTS5 (0.40) | TRPV1GAARAB9AALDH1A1CNR1 | |
| SCHEMBL17551041 | 0.70 | BACE1 (0.35) | CNR1CNR2 | |
| SCHEMBL7520459 | 0.70 | KMT2A (0.46) | GAAALDH1A1 | |
| SCHEMBL7522535 | 0.70 | CHRM3 (0.39) | TRPV1RAB9ACHRM3ALDH1A1CNR1 | |
| SCHEMBL7519913 | 0.70 | TRPV1 (0.35) | TRPV1GAARAB9ACHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699455-B1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-05-08 | — | — | EP | disclosed |