Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GNRHR | P30968 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231395 | 0.82 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL1231399 | 0.82 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL3764535 | 0.82 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1 | |
| SCHEMBL14928667 | 0.82 | HTT (0.46) | HTTGAAKDM4EUBE2NATM | |
| Hydrochloric Acid SCHEMBL525551 | 0.81 | ALDH1A1 (0.46) | GAAKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL525550 | 0.81 | ALDH1A1 (0.46) | GAAKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9216903 | 0.77 | RAB9A (0.41) | HTTRAB9AKDM4ESLC6A2SLC6A4 | |
| SCHEMBL1529695 | 0.77 | KDM4E (0.49) | HTTGAARAB9AKDM4EUBE2N | |
| SCHEMBL1529697 | 0.77 | KDM4E (0.49) | HTTGAARAB9AKDM4EUBE2N | |
| Hydrochloric Acid SCHEMBL4893319 | 0.76 | KDM4E (0.48) | HTTGAARAB9AKDM4EUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |