SCHEMBL14924580

SCHEMBL14924580

c1cc(-n2c3ccccc3c3ccccc32)cc(-n2c3ccccc3c3c4c5ccccc5n(-c5cccc(-n6c7ccccc7c7ccccc76)c5)c4ccc32)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
JAK2 O60674 1/20 0.38
JAK3 P52333 1/20 0.38
GPR3 P46089 1/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
FOLH1 Q04609 1/20 0.35
POLB P06746 2/20 0.35
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027608 0.96 L3MBTL1 (0.67) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL10027626 0.94 L3MBTL1 (0.63) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL17248327 0.91 L3MBTL1 (0.60) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL17248290 0.90 L3MBTL1 (0.69) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL12456704 0.90 L3MBTL1 (0.58) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL19359882 0.90 ATM (0.53) KDM4EL3MBTL1ATMJAK2JAK3
SCHEMBL29351958 0.89 L3MBTL1 (0.73) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL57391 0.89 L3MBTL1 (0.73) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL29371952 0.89 L3MBTL1 (0.73) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL23309001 0.89 ATM (0.52) KDM4EL3MBTL1ATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2564438-B1 DEPOSITING PREMIXED MATERIALS UNIVERSAL DISPLAY CORP (US) 2016-10-19 EP disclosed
US-9040962-B2 Depositing premixed materials UNIVERSAL DISPLAY CORPORATION (US) 2015-05-26 US disclosed
US-9040962-B2 Depositing premixed materials UNIVERSAL DISPLAY CORPORATION (US) 2015-05-26 US disclosed
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-05-09 US disclosed
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS MCM4, MCM2, MCM5 KDM4E 2235/4885L3MBTL1 2202/4885ATM 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.