Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 1/20 | 0.59 |
| ▸ | ME1 | P48163 | 1/20 | 0.59 |
| ▸ | ME3 | Q16798 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599235 | 1.00 | NPC1 (0.69) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL874261 | 0.98 | NPC1 (0.68) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7223460 | 0.92 | L3MBTL1 (0.65) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10722408 | 0.90 | HSD11B1 (0.77) | HPGDSMN1; SMN2L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL3967794 | 0.90 | HSD11B1 (0.77) | HPGDSMN1; SMN2L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL6692812 | 0.86 | NPC1 (0.58) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5267307 | 0.85 | HSD11B1 (0.70) | HPGDSMN1; SMN2L3MBTL1HSD11B1ALDH1A1 | |
| SCHEMBL8672473 | 0.84 | L3MBTL1 (0.56) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1799311 | 0.84 | POLB (0.68) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4815795 | 0.83 | NPC1 (0.51) | NPC1HPGDSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11171861-A | — | — | None | — | — | JP | disclosed |
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | NOVARTIS AG (CH) | 2024-07-25 | — | — | US | disclosed |
| US-20220111367-A1 | HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME | OSAKA UNIVERSITY (JP) | 2022-04-14 | — | — | US | disclosed |
| US-9938415-B2 | Functionalised antifouling compounds and use thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-04-10 | — | — | US | disclosed |
| US-9938415-B2 | Functionalised antifouling compounds and use thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-04-10 | — | — | US | disclosed |
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-10-27 | — | — | US | disclosed |
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| JP-H11171861-A | PRODUCTION OF DONEPEZIL | EISAI CO LTD | 1999-06-29 | — | — | JP | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0654023-B1 | 5-(2-OXYPHENYL)-PYRROLE DERIVATIVES AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5523299-A | ADMINISTERING IN TREATMENT OF PSYCHOTIC DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-04 | — | — | US | disclosed |
| EP-0654023-A1 | 5-(2-OXYPHENYL)-PYRROLE DERIVATIVES AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003426-A1 | 5-(2-OXYPHENYL)-PYRROLE DERIVATIVES AS DOPAMINE D3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311788-A1 | Antifouling Compounds And Use Thereof | C5, C9, C1S | NPC1 1720/4885HPGD 1719/4885SMN1; SMN2 3810/4885 |
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | IKZF1, IKZF2, IKZF3 | NPC1 568/4885HPGD 3215/4885SMN1; SMN2 843/4885 |
| US-20220111367-A1 | HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME | SUV39H2, SUV39H1, HRH3 | NPC1 4484/4885HPGD 444/4885SMN1; SMN2 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.