Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491307 | 0.88 | HSD17B10 (0.67) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| SCHEMBL29440302 | 0.80 | HSD17B10 (1.00) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| SCHEMBL329762 | 0.80 | HSD17B10 (1.00) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| Hydrochloric Acid SCHEMBL31670342 | 0.79 | HSD17B10 (0.97) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| SCHEMBL2978779 | 0.78 | LMNA (0.63) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| Formic Acid SCHEMBL31031810 | 0.78 | HSD17B10 (0.87) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| SCHEMBL5678241 | 0.75 | CYP1A2 (0.70) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| Acetic Acid SCHEMBL30396701 | 0.74 | LMNA (0.58) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| SCHEMBL21114783 | 0.74 | KMT2A (1.00) | HSD17B10LMNACYP1A2CYP2D6THRB | |
| Hydrochloric Acid SCHEMBL18345596 | 0.73 | KMT2A (0.97) | HSD17B10LMNACYP1A2CYP2D6THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133104-B2 | Enzyme inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2015-09-15 | — | — | US | disclosed |
| US-20140163042-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2014-06-12 | — | — | US | disclosed |
| US-20130116318-A1 | Enzyme Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116318-A1 | Enzyme Inhibitors | HDAC1, HDAC11, HDAC7 | HSD17B10 110/4885LMNA 2584/4885CYP1A2 1309/4885 |
| US-20140163042-A1 | ENZYME INHIBITORS | HAT1, NR2E1, HDAC3 | HSD17B10 84/4885LMNA 885/4885CYP1A2 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.