Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.32 |
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13000001 | 0.88 | ALOX5AP (0.33) | HSD11B1ALOX5APFEN1 | |
| SCHEMBL17359236 | 0.87 | ALOX5AP (0.33) | ALOX5APFEN1 | |
| SCHEMBL13111383 | 0.86 | DGAT1 (0.36) | ALOX5APFEN1DGAT1 | |
| SCHEMBL12658820 | 0.85 | DGAT1 (0.36) | HSD11B1SLC6A3BRD4CREBBPAKR1C3 | |
| SCHEMBL12999817 | 0.85 | HSD11B1 (0.34) | HSD11B1SLC6A3ALOX5APFEN1KDM1A | |
| SCHEMBL12856703 | 0.84 | ALOX5AP (0.36) | HSD11B1ALOX5APFEN1 | |
| SCHEMBL12205179 | 0.84 | ESR2 (0.31) | HSD11B1 | |
| SCHEMBL12999857 | 0.84 | ALOX5AP (0.35) | HSD11B1ALOX5APFEN1 | |
| SCHEMBL13225428 | 0.83 | PDE3B (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL803146 | 0.83 | ESR2 (0.41) | HSD11B1SLC6A3BRD4CREBBPAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20130114010-A1 | POLYMERISABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |