SCHEMBL14925838

SCHEMBL14925838

c1ccc2c(c1)oc1c(-c3ccc4c(c3)c3cc(-c5cccc6c5oc5ccccc56)ccc3c3nccnc43)cccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.58
PRKDC P78527 6/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
GGPS1 O95749 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.41
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
DRD4 P21917 1/20 0.36
ATM Q13315 1/20 0.36
LIMK1 P53667 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725857 0.96 ALOX5 (0.54) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL25523545 0.96 ALOX5 (0.54) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL14725861 0.96 ALOX5 (0.54) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL18777777 0.95 ALOX5 (0.53) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL11949979 0.95 ALOX5 (0.53) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL11949974 0.95 ALOX5 (0.53) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL20697876 0.95 ALOX5 (0.56) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL14925843 0.94 ALOX5 (0.58) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL18777923 0.94 ALOX5 (0.52) ALOX5PRKDCKMT2AMEN1GGPS1
SCHEMBL11949981 0.94 ALOX5 (0.52) ALOX5PRKDCKMT2AMEN1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096578-B2 Dibenzol[f,h]quinoxaline compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-04 US disclosed
US-9096578-B2 Dibenzol[f,h]quinoxaline compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-08-04 US disclosed
US-20130112954-A1 Dibenzo[f,h]Quinoxaline Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed
US-20130112954-A1 Dibenzo[f,h]Quinoxaline Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130112954-A1 Dibenzo[f,h]Quinoxaline Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device DDT, PDXK, DDX41 ALOX5 623/4885PRKDC 2999/4885KMT2A 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.