SCHEMBL14926348

SCHEMBL14926348

COCCOC(=O)C1CCC(COC)CC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PPM1B O75688 1/20 0.32
PTPN1 P18031 1/20 0.32
PPP1CC P36873 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
GAA P10253 1/20 0.31
PRKACA P17612 1/20 0.31
PRKACG P22612 1/20 0.31
PRKACB P22694 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926374 0.90 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL14926353 0.90 ALDH1A1 (0.35) ALDH1A1MEN1KMT2ASMN1; SMN2PRKACA
SCHEMBL9961300 0.89 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL14926366 0.88 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATSHRPRKACA
SCHEMBL14926351 0.86 GAA (0.37) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL17802961 0.84 MAPT (0.47) ALDH1A1MEN1KMT2AMAPTPPM1B
SCHEMBL14926378 0.83 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATSHRHPGD
SCHEMBL844650 0.83 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL845076 0.83 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL15693371 0.83 MAPT (0.38) ALDH1A1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738242-B2 Compound, cured product, polymer, photo-alignment film, optically anisotropic body and liquid crystal display element DIC CORPORATION (JP) 2020-08-11 US disclosed
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
EP-2727903-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT OF SAID POLYMER DIC Corporation (JP) 2014-05-07 EP disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738242-B2 Compound, cured product, polymer, photo-alignment film, optically anisotropic body and liquid crystal display element PYM1, ZYX, CRY1 ALDH1A1 2197/4885MEN1 2061/4885KMT2A 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.