SCHEMBL14926549

SCHEMBL14926549

Fc1cccc(-c2c(F)cc(F)cc2F)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.48
ESR2 Q92731 1/20 0.48
IDO1 P14902 2/20 0.46
NISCH Q9Y2I1 1/20 0.44
DHODH Q02127 1/20 0.42
NOTUM Q6P988 2/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
ACHE P22303 1/20 0.41
KDM4E B2RXH2 2/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26570742 0.88 TAAR1 (0.50) TAAR1ESR2IDO1NISCHNOTUM
SCHEMBL12488051 0.80 TAAR1 (0.44) TAAR1ESR2IDO1NISCHNOTUM
SCHEMBL25270075 0.80 MAOA (0.50) TAAR1KDM4EMEN1MAPTKMT2A
SCHEMBL23174839 0.80 TYMP (0.42) ESR2DHODHMAPTALDH1A1
SCHEMBL29656866 0.79 TAAR1 (0.47) TAAR1ESR2IDO1NISCHDHODH
SCHEMBL198702 0.79 TAAR1 (0.68) TAAR1ESR2IDO1NISCHNOTUM
SCHEMBL17082215 0.77 TAAR1 (0.60) TAAR1ESR2IDO1NISCHNOTUM
SCHEMBL20022105 0.77 ACHE (0.48) IDO1NISCHDHODHACHE
SCHEMBL20022144 0.77 ACHE (0.48) IDO1NISCHDHODHACHE
SCHEMBL28468561 0.77 TAAR1 (0.38) TAAR1ESR2IDO1NISCHDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130114009-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-09 US disclosed