Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12072675 | 0.91 | PDE10A (0.43) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL14903970 | 0.81 | PDE10A (0.40) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL14926990 | 0.78 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DCYP11B1 | |
| SCHEMBL14926984 | 0.77 | PDCD1 (0.47) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL14926972 | 0.76 | ESR1 (0.39) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL14903982 | 0.74 | PDGFRB (0.53) | ALDH1A1CYP11B1CYP11B2MTNR1AMTNR1B | |
| SCHEMBL14903974 | 0.73 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DCYP11B1 | |
| SCHEMBL12070517 | 0.72 | USP2 (0.44) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12074762 | 0.72 | PDE10A (0.43) | USP2CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL12072698 | 0.69 | SMN1; SMN2 (0.48) | USP2CYP1A2CYP3A4CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | USP2 4630/4885CYP1A2 2201/4885CYP3A4 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.