Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | PDE1A | P54750 | 4/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 7/20 | 0.34 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16510622 | 0.89 | CTDSP1 (0.37) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14927042 | 0.87 | FYN (0.35) | FYNIKBKBMEN1ALDH1A1KMT2A | |
| SCHEMBL14904334 | 0.84 | FYN (0.34) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14926992 | 0.71 | PTAFR (0.51) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903984 | 0.71 | FYN (0.38) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903983 | 0.70 | PDGFRB (0.54) | FYN | |
| SCHEMBL128807 | 0.69 | RAC1 (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14903985 | 0.69 | MTNR1A (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14904027 | 0.68 | PDCD1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14904013 | 0.67 | PTPN1 (0.39) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | PDE5A 2129/4885PDE4A 2153/4885PDE4B 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.