Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931874 | 0.69 | MEN1 (0.36) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL6586181 | 0.68 | — | — | |
| SCHEMBL12264200 | 0.67 | IDO1 (0.39) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL21215483 | 0.64 | IDO1 (0.52) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL12213708 | 0.64 | — | — | |
| SCHEMBL13179482 | 0.64 | BRD4 (0.32) | MEN1KMT2ACYP1A2CYP3A4HTR2C | |
| SCHEMBL24119411 | 0.64 | GRM1 (0.41) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL7739423 | 0.63 | IDO1 (0.36) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL7028419 | 0.63 | IDO1 (0.36) | MEN1KMT2AMAOASLC6A2CYP1A2 | |
| SCHEMBL7022756 | 0.63 | IDO1 (0.36) | MEN1KMT2AMAOASLC6A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722900-B2 | Process for cabazitaxel, and intermediates thereof | SCINOPHARM TAIWAN, LTD. (TW) | 2014-05-13 | — | — | US | disclosed |
| US-20130116444-A1 | PROCESS FOR CABAZITAXEL, AND INTERMEDIATES THEREOF | SCINOPHARM TAIWAN, LTD. (TW) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116444-A1 | PROCESS FOR CABAZITAXEL, AND INTERMEDIATES THEREOF | WEE1, XPO5, XPOT | MEN1 2292/4885KMT2A 2018/4885MAOA 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.