Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105647 | 0.89 | KDM4E (0.50) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL612628 | 0.86 | KDM4E (0.48) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL10118412 | 0.85 | KDM4E (0.47) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL13645489 | 0.78 | KDM4E (0.64) | KDM4EPOLBRECQLSMN1; SMN2MAPT | |
| SCHEMBL12201138 | 0.76 | KDM4E (0.59) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL13686278 | 0.76 | KDM4E (0.62) | KDM4EPOLBRECQL | |
| SCHEMBL16450366 | 0.75 | KDM4E (0.57) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL12201171 | 0.74 | KDM4E (0.58) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL26662987 | 0.74 | KDM4E (0.58) | KDM4EPOLBRECQLSMN1; SMN2KMT2A | |
| SCHEMBL12201165 | 0.74 | KDM4E (0.58) | KDM4EPOLBRECQLSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674102-B2 | Fluorescent dyes | ENZO LIFE SCIENCES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130217059-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130209994-A1 | FLUORESCENT DYES | ENZO LIFE SCIENCES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8476443-B2 | Fluorescent dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20130115651-A1 | FLUORESCENT DYES | ENZO BIOCHEM, INC. (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130115651-A1 | FLUORESCENT DYES | ANXA5, SSBP1, IARS1 | KDM4E 4262/4885POLB 696/4885RECQL 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.