SCHEMBL14930

SCHEMBL14930

C=CC(=O)OCC(O)CS(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 5/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 3/20 0.39
HSD17B10 Q99714 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 2/20 0.36
MAPK1 P28482 1/20 0.36
THRB P10828 2/20 0.31
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038111 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5689041 0.88 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL38666446 0.82 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL95157 0.82 TSHR (0.64) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28652916 0.81 TSHR (0.41) TSHR
SCHEMBL28652917 0.81 TSHR (0.41) TSHR
SCHEMBL9561637 0.80 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28190666 0.79 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL252054 0.79 GSTP1 (0.32) TSHRALDH1A1HPGD
SCHEMBL2210403 0.79 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728512-B1 AQUEOUS FORMULATIONS OF SURFACTANTS AND ASSOCIATIVE POLYMERS FOR THE ASSISTED RECOVERY OF PETROLEUM ENERGY SOLUTIONS US LLC (US) 2024-07-03 EP claimed
CN-114127135-B Process for preparing aqueous polymer dispersions 巴斯夫欧洲公司 2024-05-31 CN claimed
CN-114080155-B Shear stable composition for spray drift control 巴斯夫欧洲公司 2024-03-26 CN claimed
CN-115785331-B Preparation method and application of acrylate emulsion 万华化学集团股份有限公司 2024-02-27 CN claimed
CN-111566184-B Aqueous formulations of surfactants and associative polymers for assisting in the recovery of petroleum 罗地亚经营管理公司 2023-08-01 CN claimed
CN-115785331-A Preparation method and application of acrylate emulsion 万华化学集团股份有限公司 2023-03-14 CN claimed
US-20220295785-A1 SHEAR STABLE COMPOSITION FOR SPRAY DRIFT CONTROL BASF SE (DE) 2022-09-22 US claimed
US-11421147-B2 Aqueous formulations of surfactants and associative polymers for the assisted recovery of petroleum RHODIA OPERATIONS (FR) 2022-08-23 US claimed
US-11384278-B2 2022-07-12 US claimed
EP-3996504-A1 SHEAR STABLE COMPOSITION FOR SPRAY DRIFT CONTROL BASF SE (DE) 2022-05-18 EP claimed
CN-1829841-A Aqueous composition and use thereof for paper production BASF AG (DE) 2006-09-06 CN claimed
US-20060183822-A1 Ampholytic copolymer and use thereof BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 US claimed
EP-1654419-A1 AQUEOUS COMPOSITION AND USE THEREOF FOR PAPER PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 2006-05-10 EP claimed
CN-1756780-A Ampholytic copolymer and use thereof BASF AG (DE) 2006-04-05 CN claimed
US-20060037725-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-23 US claimed
US-20060024262-A1 Aqueous composition and use thereof for paper production BASF AKTIENGESELLSCHAFT (DE) 2006-02-02 US claimed
WO-2005012637-A1 AQUEOUS COMPOSITION AND USE THEREOF FOR PAPER PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 2005-02-10 WO claimed
US-6624205-B2 Cation exchanger, process for producing same, and its use TOSOH CORPORATION (JP) 2003-09-23 US claimed
US-20020103265-A1 Cation exchanger, process for producing same, and its use TOSOH CORPORATION 2002-08-01 US claimed
EP-1226869-A2 Cation exchanger, process for producing same, and its use TOSOH CORPORATION (JP) 2002-07-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220295785-A1 SHEAR STABLE COMPOSITION FOR SPRAY DRIFT CONTROL PLD1, PFN1, SPIN1 TSHR 4037/4885ALDH1A1 3365/4885TP53 3407/4885
US-20060024262-A1 Aqueous composition and use thereof for paper production CHMP4B, AQP1, IL17A TSHR 4840/4885ALDH1A1 3860/4885TP53 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.