SCHEMBL14930446

SCHEMBL14930446

CNC(=O)/C=C/c1ccc(C)c(OC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.55
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 1/20 0.53
STAT1 P42224 1/20 0.53
RAB9A P51151 1/20 0.53
HPGD P15428 3/20 0.53
CYP1A2 P05177 3/20 0.53
HSD17B10 Q99714 3/20 0.53
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
ALOX15 P16050 2/20 0.53
MAPK1 P28482 2/20 0.53
CYP2D6 P10635 3/20 0.52
KDM1A O60341 3/20 0.52
CYP2C9 P11712 2/20 0.52
TSHR P16473 2/20 0.52
HDAC3 O15379 2/20 0.52
TYR P14679 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13226382 1.00 NFE2L2 (0.55) NFE2L2KMT2AMEN1SMN1; SMN2NPC1
SCHEMBL10726474 0.85 KDM1A (0.73) NFE2L2KMT2AMEN1HPGDCYP1A2
SCHEMBL14495458 0.84 NFE2L2 (0.77) NFE2L2KMT2AMEN1HPGDCYP1A2
SCHEMBL1204566 0.84 EPHX2 (0.72) NFE2L2KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL1204568 0.84 EPHX2 (0.72) NFE2L2KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL1204552 0.83 KDM4E (0.76) NFE2L2KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL14930493 0.83 APP (0.71) NFE2L2KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL1204551 0.83 KDM4E (0.76) NFE2L2KMT2AMEN1SMN1; SMN2HPGD
SCHEMBL14926735 0.82 PELI1 (0.52) KMT2AMEN1SMN1; SMN2CYP1A2KDM4E
SCHEMBL21986836 0.81 KDM4E (0.59) NFE2L2KMT2AMEN1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed