SCHEMBL1204552

SCHEMBL1204552

COc1cc(C=CC(=O)O)ccc1C

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.76
ALDH1A1 P00352 5/20 0.76
SMN1; SMN2 Q16637 3/20 0.76
HPGD P15428 2/20 0.76
HSD17B10 Q99714 2/20 0.76
ALOX15 P16050 1/20 0.76
MAPK1 P28482 1/20 0.76
PKM P14618 2/20 0.71
SNCA P37840 2/20 0.71
CA12 O43570 1/20 0.71
CA1 P00915 1/20 0.71
CA2 P00918 1/20 0.71
CA3 P07451 1/20 0.71
CSNK2A2 P19784 1/20 0.71
CA4 P22748 1/20 0.71
CA6 P23280 1/20 0.71
CA5A P35218 1/20 0.71
CA7 P43166 1/20 0.71
CSNK2B P67870 1/20 0.71
CSNK2A1 P68400 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204551 1.00 KDM4E (0.76) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL14930493 0.87 APP (0.71) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL5218481 0.87 ALDH1A1 (0.76) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL5218471 0.87 ALDH1A1 (0.76) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL31501092 0.87 ALDH1A1 (0.76) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
O,O'-Dimethylcaffeic Acid SCHEMBL29636389 0.86 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
O,O'-Dimethylcaffeic Acid SCHEMBL81317 0.86 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
O,O'-Dimethylcaffeic Acid SCHEMBL81318 0.86 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL14495458 0.85 NFE2L2 (0.77) KDM4EALDH1A1HPGDHSD17B10ALOX15
SCHEMBL21986836 0.85 KDM4E (0.59) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081932-A1 RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市护家科技有限公司 2025-04-24 WO claimed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN claimed
CN-115490800-B Filtrate reducer and preparation method and application thereof 山东诺尔生物科技有限公司 2024-02-13 CN claimed
CN-115490800-A Filtrate reducer and preparation method and application thereof 山东诺尔生物科技有限公司 2022-12-20 CN claimed
WO-2025081932-A1 RETINOL DERIVATIVE OR SALT THEREOF, AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市护家科技有限公司 2025-04-24 WO disclosed
CN-119841755-A Retinol derivative or its salt, and preparation method and application thereof 深圳市护家科技有限公司 2025-04-18 CN disclosed
CN-117653618-A Novel benzalacetone derivative and use thereof 韩药有限公司 2024-03-08 CN disclosed
CN-115490800-B Filtrate reducer and preparation method and application thereof 山东诺尔生物科技有限公司 2024-02-13 CN disclosed
CN-110996930-B Novel benzalacetone derivative and use thereof 韩药有限公司 2024-02-02 CN disclosed
CN-115490800-A Filtrate reducer and preparation method and application thereof 山东诺尔生物科技有限公司 2022-12-20 CN disclosed
CN-110996930-A Novel benzylidene acetone derivative and use thereof 韩药有限公司 2020-04-10 CN disclosed
EP-1963304-B2 ISOQUINOLINE DERIVATIVES MSD OSS BV (NL) 2015-05-13 EP disclosed
EP-0996621-A1 NOVEL COMPOUNDS Astra Pharmaceuticals Limited (GB) 2000-05-03 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed
EP-0944386-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-09-29 EP disclosed
WO-1999005143-A1 NOVEL COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1999-02-04 WO disclosed
WO-1998025611-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-18 WO disclosed
EP-0249301-B1 Pyrido[2,3-b]indoles BEECHAM GROUP PLC (GB) 1992-05-27 EP disclosed
US-4952584-A TREATMENT OF PROPHYLAXIS OF ANXIETY OR DEPRESSION BEECHAM GROUP P.L.C. (GB) 1990-08-28 US disclosed
EP-0249301-A1 Pyrido[2,3-b]indoles BEECHAM GROUP PLC (GB) 1987-12-16 EP disclosed