SCHEMBL1493080

SCHEMBL1493080

O=C=Nc1cccc(N=C=O)c1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.54
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
TRPA1 O75762 1/20 0.34
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1161021 0.88 CYP3A4 (0.47) CYP3A4GABRA1GABRB2TRPA1
SCHEMBL4242346 0.88 CYP3A4 (0.47) CYP3A4GABRA1GABRB2TRPA1
SCHEMBL964183 0.87 CYP3A4 (0.55) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL3240712 0.87 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1
SCHEMBL1133625 0.87 CYP3A4 (0.46) CYP3A4GABRA1GABRB2TRPA1TDP1
SCHEMBL11872591 0.80 CYP3A4 (0.56) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL11871641 0.78 CYP3A4 (0.54) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL28258602 0.78 CYP3A4 (0.59) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL29648814 0.77 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1TDP1
SCHEMBL75112 0.77 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9153843-B2 Negative electrode including solid electrolyte interface coating containing crosslinked isocyanate compound, nonaqueous electrolyte secondary battery and method for manufacturing the same SONY CORPORATION (JP) 2015-10-06 US disclosed
CN-102597274-A Soil and stain resistant coating composition for finished leather substrates 3M INNOVATIVE PROPERTIES CO 2012-07-18 CN disclosed
CN-101490135-B Fluorochemical composition comprising fluorinated oligomeric silane 3M INNOVATIVE PROPERTIES CO 2012-07-04 CN disclosed
CN-102317234-A Be used for providing the compsn and the method for spot detachability or pollution resistance to base material 3M INNOVATIVE PROPERTIES CO 2012-01-11 CN disclosed
CN-102317235-A The compsn and the method for greasiness removal and pollution resistance are provided for substrate 3M INNOVATIVE PROPERTIES CO 2012-01-11 CN disclosed
US-20110052953-A1 NEGATIVE ELECTRODE, NONAQUEOUS ELECTROLYTE SECONDARY BATTERY AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-03-03 US disclosed