SCHEMBL14930895

SCHEMBL14930895

O=P(O)(O)OCC1OCCC1OP(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.46
INPP5A Q14642 2/20 0.37
IGF2R P11717 4/20 0.34
AMDHD2 Q9Y303 1/20 0.34
PGD P52209 1/20 0.34
P2RY1 P47900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17586041 0.86 FBP1 (0.33) FBP1INPP5APGD
SCHEMBL481700 0.82 INPP5A (0.39) INPP5A
SCHEMBL15492995 0.82 INPP5A (0.39) INPP5A
SCHEMBL19464721 0.82 INPP5A (0.39) INPP5A
SCHEMBL432511 0.82 INPP5A (0.39) INPP5A
SCHEMBL10023962 0.82 INPP5A (0.39) INPP5A
SCHEMBL15490035 0.80 FBP1 (0.33) FBP1AMDHD2
SCHEMBL22946277 0.80 SMN1; SMN2 (0.37) INPP5A
SCHEMBL20799471 0.79 IGF2R (0.37) FBP1IGF2R
SCHEMBL20673343 0.79 FBP1 (0.53) FBP1IGF2RAMDHD2PGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9428535-B2 Modified nucleosides, nucleotides, and nucleic acids, and uses thereof MODERNA THERAPEUTICS, INC. (US) 2016-08-30 US disclosed
US-20130115272-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF modeRNA Therapeutics (US) 2013-05-09 US disclosed