SCHEMBL1493178

SCHEMBL1493178

NCCCCNc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
MAPT P10636 1/20 0.70
HDAC3 O15379 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
MAOA P21397 1/20 0.46
PRSS1 P07477 5/20 0.44
F2 P00734 2/20 0.42
PRSS2 P07478 2/20 0.42
PRSS3 P35030 2/20 0.42
TMPRSS6 Q8IU80 2/20 0.42
ST14 Q9Y5Y6 2/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIA1 P42261 1/20 0.42
GRIA2 P42262 1/20 0.42
GRIA3 P42263 1/20 0.42
GRIA4 P48058 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7201128 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL9530147 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL1296795 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL1537234 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL21224348 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL21799841 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL21799543 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL21799912 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
SCHEMBL21800026 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL28582360 0.98 ALDH1A1 (0.67) ALDH1A1MAPTHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118755080-A Preparation method of polyamide 66 with high strength and high elongation at break 江苏扬农化工集团有限公司 2024-10-11 CN claimed
CN-114507164-B Gemini surfactant, preparation method, composition and application thereof 中国石油天然气股份有限公司 2023-10-24 CN claimed
CN-116410101-A Asymmetric Gemini surfactant, preparation method and application thereof 中国石油天然气股份有限公司 2023-07-11 CN claimed
CN-114507164-A Gemini surfactant, preparation method, composition and application thereof 中国石油天然气股份有限公司 2022-05-17 CN claimed
US-20260108521-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2026-04-23 US disclosed
EP-4598918-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2025-08-13 EP disclosed
CN-116410101-B Asymmetric Gemini surfactant, preparation method and application thereof 中国石油天然气股份有限公司 2025-02-28 CN disclosed
CN-118755080-A Preparation method of polyamide 66 with high strength and high elongation at break 江苏扬农化工集团有限公司 2024-10-11 CN disclosed
EP-3623398-B1 RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER ASAHI CHEMICAL IND (JP) 2024-08-28 EP disclosed
WO-2024073871-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2024-04-11 WO disclosed
CN-114507164-B Gemini surfactant, preparation method, composition and application thereof 中国石油天然气股份有限公司 2023-10-24 CN disclosed
CN-116410101-A Asymmetric Gemini surfactant, preparation method and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed
WO-2004033465-A1 2' OXO-VORUSCHARIN AND DERIVATIVES THEREOF UNIBIOSCREEN S.A. (BE) 2004-04-22 WO disclosed
EP-1408043-A1 2''oxo-voruscharin and analogues thereof Unibioscreen S.A. (BE) 2004-04-14 EP disclosed
WO-2003049746-A2 COMBINATION OF CYTOCHOME P450 DEPENDENT PROTEASE INHIBITORS TIBOTEC PHARMACEUTICALS LTD. (IE) 2003-06-19 WO disclosed
EP-1088098-A2 FITNESS ASSAY AND ASSOCIATED METHODS UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND SOCIAL SERVICES (US) 2001-04-04 EP disclosed
WO-1999067254-A2 MULTI-DRUG RESISTANT RETROVIRAL PROTEASE INHIBITORS AND USE THEREOF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-29 WO disclosed
WO-1999067417-A2 FITNESS ASSAY AND ASSOCIATED METHODS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-29 WO disclosed
US-4995997-A Containing aromatic amine YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 1991-02-26 US disclosed
EP-0388320-A1 Antibacterial water-soluble cutting fluids resistant to yeast-like fungi YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) 1990-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108521-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME GHSR, GSPT1, GLRA1 ALDH1A1 3997/4885MAPT 910/4885HDAC3 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.