Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434635 | 0.78 | CSNK1A1 (0.39) | CSNK1A1CLK4ADORA2AADORA1CDK1 | |
| SCHEMBL12726136 | 0.75 | CSNK1A1 (0.37) | CSNK1A1CLK4ADORA2AADORA1CDK1 | |
| SCHEMBL584580 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1TSHR | |
| SCHEMBL12726137 | 0.75 | CSNK1A1 (0.46) | CSNK1A1CLK4ADORA2AADORA1CDK1 | |
| SCHEMBL19100200 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4ADORA2AADORA1KDM4E | |
| SCHEMBL2872592 | 0.72 | CSNK1A1 (0.35) | CSNK1A1CLK4ADORA2AADORA1CDK1 | |
| SCHEMBL21550205 | 0.72 | GAA (0.44) | CSNK1A1CLK4KDM4EMEN1GAA | |
| SCHEMBL17816473 | 0.72 | CDK1 (0.45) | CSNK1A1CLK4ADORA2AADORA1CDK1 | |
| SCHEMBL14932514 | 0.71 | MBOAT4 (0.43) | CSNK1A1CLK4HTT | |
| SCHEMBL25786542 | 0.71 | KDM4E (0.36) | CSNK1A1CLK4ADORA2AADORA1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067142-A1 | COMPOUNDS AND TREATMENT METHODS | MEDIVATION TECHNOLOGIES, INC. (US) | 2013-05-10 | — | — | WO | disclosed |