Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434635 | 0.78 | CSNK1A1 (0.39) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL263835 | 0.78 | CSNK1A1 (0.64) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL14932504 | 0.75 | CSNK1A1 (0.37) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL12726137 | 0.75 | CSNK1A1 (0.46) | CSNK1A1CLK4KDM4ETSHRL3MBTL1 | |
| SCHEMBL12726136 | 0.75 | CSNK1A1 (0.37) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL1143429 | 0.75 | CSNK1A1 (1.00) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL19837459 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL1143690 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL28939398 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4KDM4EGAAKMT2A | |
| SCHEMBL31492947 | 0.75 | CSNK1A1 (0.60) | CSNK1A1CLK4KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751436-A | Method for efficiently preparing vitamin B1 | 云鹏医药集团有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-112851588-B | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same | 复旦大学 | 2023-04-21 | — | — | CN | claimed |
| US-11554355-B2 | Micro reaction system and method for preparing 2-methyl-4-amino-5-cyanopyrimidine using same | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| US-11554356-B2 | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethylpyrimidine | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| US-11554354-B2 | Micro-reaction system and method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| CN-112341395-B | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-aminomethyl pyrimidine by using same | 复旦大学 | 2022-06-21 | — | — | CN | claimed |
| US-20210394150-A1 | FULL CONTINUOUS FLOW PREPARATION METHOD OF 2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UNIV FUDAN (CN) | 2021-12-23 | — | — | US | claimed |
| US-20210394148-A1 | MICRO-REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE | FUDAN UNIVERSITY (CN) | 2021-12-23 | — | — | US | claimed |
| US-20210394149-A1 | MICRO REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-CYANOPYRIMIDINE USING SAME | FUDAN UNIVERSITY (CN) | 2021-12-23 | — | — | US | claimed |
| CN-113121449-A | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethyl pyrimidine | 复旦大学 | 2021-07-16 | — | — | CN | claimed |
| CN-112851588-A | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same | 复旦大学 | 2021-05-28 | — | — | CN | claimed |
| CN-112341395-A | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-aminomethyl pyrimidine by using same | 复旦大学 | 2021-02-09 | — | — | CN | claimed |
| CN-111018836-A | Pyrimidine preparation with synergistic sulfonamide effect and preparation method thereof | 南京福斯特牧业科技有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-106279042-B | The method for preparing 2- methyl -4- amino-5-cyanopyrimidine is reacted using Mannich | 新发药业有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-106008363-B | The preparation method of 2- methyl -4- amino-5-cyanopyrimidines | 新发药业有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-105254574-B | A kind of simple and convenient process for preparing of the cyanopyrimidine of 2 methyl of vitamin B1 key intermediate, 4 amino 5 | 新发药业有限公司 | 2017-11-14 | — | — | CN | claimed |
| CN-106279042-A | The method utilizing Mannich reaction preparation 2 methyl 4 amino 5 cyanopyrimidines | 新发药业有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-106008363-A | Environment-friendly preparation method of 2-methyl-4-amino-5-cyanopyrimidine | 新发药业有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-105254574-A | Simple preparation method of vitamin B1 key intermediate 2-methyl-4-amidogen-5-cyanopyrimidine | XINFA PHARMACEUTICAL CO LTD | 2016-01-20 | — | — | CN | claimed |
| US-4256550-A | ELECTROCHEMICAL OXIDATION AND REDUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210394148-A1 | MICRO-REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE | DPYD, HNMT, KIT | CSNK1A1 3569/4885CLK4 1336/4885KDM4E 797/4885 |
| US-20210394150-A1 | FULL CONTINUOUS FLOW PREPARATION METHOD OF 2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | MCM4, NUDT1, CMPK1 | CSNK1A1 966/4885CLK4 67/4885KDM4E 287/4885 |
| US-20210394149-A1 | MICRO REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-CYANOPYRIMIDINE USING SAME | DPYD, MCM4, UMPS | CSNK1A1 3015/4885CLK4 299/4885KDM4E 950/4885 |
| US-11554356-B2 | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethylpyrimidine | MCM4, NUDT1, CMPK1 | CSNK1A1 966/4885CLK4 67/4885KDM4E 287/4885 |
| US-11554355-B2 | Micro reaction system and method for preparing 2-methyl-4-amino-5-cyanopyrimidine using same | DPYD, MCM4, UMPS | CSNK1A1 3015/4885CLK4 299/4885KDM4E 950/4885 |
| US-11554354-B2 | Micro-reaction system and method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine | DPYD, HNMT, KIT | CSNK1A1 3569/4885CLK4 1336/4885KDM4E 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.