Sugi Predict

Sugi Predict / Compounds / SCHEMBL14933305

SCHEMBL14933305

SCHEMBL14933305

CC1(C)c2ccccc2-c2cc3c(cc21)c(=O)n(-c1ccccc1)c1ccc(-c2ccc4c(c2)c2ccccc2n4-c2ccccc2)cc31

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ GLA P06280 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ PGR P06401 5/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ BRCA1 P38398 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ MAPK8 P45983 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ TSPO P30536 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933308 0.94 KMT2A (0.38) KMT2AKDM4EALDH1A1CYP1A2GLA
SCHEMBL14933548 0.90 MAPK1 (0.40) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL23259728 0.89 KDM4E (0.40) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL23259730 0.89 KDM4E (0.40) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL17878954 0.89 KDM4E (0.40) KDM4EATML3MBTL1PGRTSPO
SCHEMBL17878941 0.89 KDM4E (0.40) KDM4EATML3MBTL1PGRTSPO
SCHEMBL29694589 0.89 L3MBTL1 (0.44) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL10001493 0.89 L3MBTL1 (0.44) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL15946303 0.89 L3MBTL1 (0.44) KMT2AKDM4EATML3MBTL1ALDH1A1
SCHEMBL15338025 0.89 L3MBTL1 (0.44) KMT2AKDM4EATML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 — — EP disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 — — US disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 — — WO disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 — — US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 — — US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 — — EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 — — US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 — — US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KMT2A 3888/4885KDM4E 3376/4885ATM 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.