SCHEMBL14933377

SCHEMBL14933377

O=c1c2c(ccc3c2c2ccccc2n3-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c2ccccc2n1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 5/20 0.39
HKDC1 Q2TB90 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
BRCA1 P38398 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RXFP1 Q9HBX9 2/20 0.39
MAPK8 P45983 2/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828786 0.93 KMT2A (0.41) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL25829019 0.91 KMT2A (0.41) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL24597890 0.89 KMT2A (0.43) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL25828637 0.89 KMT2A (0.41) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL18020052 0.88 KMT2A (0.44) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL15073468 0.87 L3MBTL1 (0.47) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL12131955 0.87 L3MBTL1 (0.50) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL25830604 0.87 KMT2A (0.42) KMT2AMEN1NPC1LMNARAB9A
SCHEMBL20633670 0.86 ALDH1A1 (0.43) KMT2AMEN1LMNAKDM4EATM
SCHEMBL24597939 0.86 KMT2A (0.41) KMT2AMEN1NPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed
WO-2021052924-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-03-25 WO disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KMT2A 3888/4885MEN1 2556/4885NPC1 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.