SCHEMBL14933429

SCHEMBL14933429

O=c1oc2cccc3c2c2c1cccc2c(=O)n3-c1cccc(-c2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.42
BRCA1 P38398 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.40
PDE10A Q9Y233 1/20 0.39
PLA2G2A P14555 2/20 0.39
PLA2G4A P47712 2/20 0.39
NQO1 P15559 1/20 0.38
CA9 Q16790 2/20 0.38
FAAH O00519 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
MGLL Q99685 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933427 0.88 KMT2A (0.42) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14933495 0.83 ALDH1A1 (0.48) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14933410 0.80 KMT2A (0.47) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL16925812 0.79 TDP1 (0.43) ALDH1A1LMNAPLA2G2APLA2G4ANQO1
SCHEMBL14933515 0.79 KMT2A (0.48) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL16925679 0.77 L3MBTL1 (0.44) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14933435 0.77 KMT2A (0.50) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14933413 0.77 KMT2A (0.50) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL14933618 0.77 KMT2A (0.43) KMT2AMEN1ALDH1A1POLBTSHR
SCHEMBL18967707 0.77 KDM4E (0.40) KMT2AMEN1ALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed