SCHEMBL14933547

SCHEMBL14933547

CC1(C)c2ccccc2-c2cc3c(cc21)c(=O)n(-c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1ccccc31

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
PGR P06401 5/20 0.34
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
BRCA1 P38398 1/20 0.34
PDE10A Q9Y233 1/20 0.34
KDM4E B2RXH2 3/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
GSK3B P49841 1/20 0.33
BRD4 O60885 1/20 0.32
CAMK2D Q13557 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933544 0.88 MAPK1 (0.36) KMT2APGRHSD17B10PDE10AGSK3B
SCHEMBL14933565 0.87 KMT2A (0.34) KMT2APGRALDH1A1HSD17B10MEN1
SCHEMBL17070993 0.87 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL782283 0.86 KDM4E (0.37) PGRHSD17B10KDM4EGSK3BATM
SCHEMBL16176129 0.86 KDM4E (0.37) PGRHSD17B10KDM4EGSK3BATM
SCHEMBL18518703 0.85 KDM4E (0.36) PGRKDM4EGSK3BATML3MBTL1
SCHEMBL17245600 0.85 KDM4E (0.36) PGRKDM4EGSK3BATML3MBTL1
SCHEMBL14933305 0.85 KMT2A (0.39) KMT2APGRALDH1A1HSD17B10MEN1
SCHEMBL14933308 0.84 KMT2A (0.38) KMT2APGRALDH1A1HSD17B10MEN1
SCHEMBL14933583 0.84 BRD4 (0.33) KMT2APGRPDE10AGSK3BBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KMT2A 3888/4885PGR 1967/4885ALDH1A1 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.