SCHEMBL14933583

SCHEMBL14933583

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5ccccc5c(=O)n6-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)ccc4n(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c3cc21

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 5/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 1/20 0.32
PDE10A Q9Y233 1/20 0.32
PIM1 P11309 1/20 0.32
PGR P06401 1/20 0.32
TYMS P04818 1/20 0.31
TSPO P30536 1/20 0.31
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933306 0.94 KMT2A (0.36) BRD4KMT2AMAPK1PDE10APIM1
SCHEMBL14933544 0.94 MAPK1 (0.36) BRD4KMT2AMAPK1PDE10APGR
SCHEMBL14933565 0.92 KMT2A (0.34) BRD4KMT2AMAPK1PDE10APGR
SCHEMBL16076349 0.92 PDK2 (0.31) TSPO
SCHEMBL14886354 0.92 PDK2 (0.31) TSPO
SCHEMBL14933548 0.92 MAPK1 (0.40) BRD4KMT2AMAPK1PGR
SCHEMBL17229932 0.92 PDK2 (0.33) PGRTSPO
SCHEMBL15946323 0.91 TSPO (0.35) TSPOGSK3B
SCHEMBL20632549 0.90 KMT2A (0.36) BRD4KMT2AMAPK1PDE10APGR
SCHEMBL18518997 0.90 PGR (0.33) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 BRD4 2427/4885KMT2A 3888/4885MAPK1 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.