Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814551 | 0.85 | PRMT5 (0.34) | PAK1MAP2K4DYRK1APRMT5WDR77 | |
| SCHEMBL14933629 | 0.80 | FAAH (0.42) | PIM1ALOX15MEN1MAPTKMT2A | |
| SCHEMBL14919956 | 0.77 | MAPT (0.32) | ALOX15MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL16011441 | 0.77 | MAP2K4 (0.39) | PAK1MAPTMAP2K4DYRK1APRMT5 | |
| SCHEMBL19100167 | 0.72 | KDM4E (0.46) | MAPTHPGDMAP2K4ALDH1A1HTT | |
| SCHEMBL29431300 | 0.72 | KDM4E (0.46) | MAPTHPGDMAP2K4ALDH1A1HTT | |
| SCHEMBL16021936 | 0.68 | HDAC1 (0.36) | ALOX15MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL16021942 | 0.67 | FAAH (0.35) | KMT2AALDH1A1PDPK1 | |
| SCHEMBL19392330 | 0.67 | RECQL (0.34) | ALOX15MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL16021506 | 0.67 | MAP2K4 (0.40) | PAK1MAPTMAPK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064984-A1 | BIARYL ETHER SULFONAMIDES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |