Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18577157 | 0.88 | MAOB (0.48) | MEN1KMT2ASIGMAR1HTR1AMAOB | |
| SCHEMBL18577156 | 0.88 | MAOB (0.48) | MEN1KMT2ASIGMAR1HTR1AMAOB | |
| SCHEMBL18707313 | 0.81 | OXTR (0.49) | OXTRPNMT | |
| SCHEMBL18706942 | 0.81 | OXTR (0.49) | OXTRPNMT | |
| SCHEMBL18707169 | 0.81 | OXTR (0.49) | OXTRPNMT | |
| SCHEMBL13091464 | 0.81 | OXTR (0.44) | OXTRPNMT | |
| SCHEMBL17957834 | 0.80 | LTB4R (0.54) | MEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL17957836 | 0.80 | LTB4R (0.54) | MEN1KMT2ALTB4RLTB4R2 | |
| Hydrochloric Acid SCHEMBL18706730 | 0.79 | OXTR (0.47) | MEN1KMT2AOXTRPNMT | |
| Hydrochloric Acid SCHEMBL18706732 | 0.79 | OXTR (0.47) | MEN1KMT2AOXTRPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013064231-A1 | SEVEN-MEMBERED SULFONAMIDES AS MODULATORS OF RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORγ, NR1F3) | PHENEX PHARMACEUTICALS AG (DE) | 2013-05-10 | — | — | WO | disclosed |